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Tamm-Horsfall protein in the glomerular capsular space
- Source :
- Journal of clinical pathology. 31(7)
- Publication Year :
- 1978
-
Abstract
- Tamm-Horsfall protein was detected within the capsular space by immunofluorescence in 7 of 72 consecutive patients on whom renal immunopathological studies were performed. Three patients showed prominent aggregates or crescentic collections affecting 30-50% glomeruli; the remaining four patients showed smaller aggregates between lobules. All patients showed pathological evidence of tubulointerstitial disease. It is suggested that Tamm-Horsfall protein in the capsular space is a sign of intratubular urinary backflow and that Tamm-Horsfall antiserum is a useful addition to the reagents used in the immunofluorescence study of renal biopsies.
- Subjects :
- Adult
Male
Pathology
medicine.medical_specialty
Tamm–Horsfall protein
Mucoproteins
Urinary system
Kidney Glomerulus
Fluorescent Antibody Technique
Immunofluorescence
Pathology and Forensic Medicine
medicine
Humans
Pathological
Antiserum
medicine.diagnostic_test
biology
General Medicine
Middle Aged
biology.protein
Female
Kidney Diseases
Tubulointerstitial Disease
Research Article
Subjects
Details
- ISSN :
- 00219746
- Volume :
- 31
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- Journal of clinical pathology
- Accession number :
- edsair.doi.dedup.....da84ba6c7fa12cd7271f7874f2464891