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Macrolide Resistance in Peptostreptococcus spp. Mediated by ermTR: Possible Source of Macrolide-Lincosamide-Streptogramin B Resistance in Streptococcus pyogenes
- Publication Year :
- 2001
- Publisher :
- American Society for Microbiology, 2001.
-
Abstract
- Eighty percent (21 of 26) of macrolide-resistant Peptostreptococcus strains studied harbored the ermTR gene. This methyltransferase gene is also the most frequently found gene among macrolide-lincosamide-streptogramin B-resistant Streptococcus pyogenes strains. Transfer of the ermTR gene from Peptostreptococcus magnus to macrolide-susceptible S. pyogenes strains indicates that this resistance determinant may circulate among gram-positive aerobic and anaerobic species of the oropharyngeal bacterial flora.
- Subjects :
- Streptogramins
medicine.drug_class
Streptococcus pyogenes
medicine.disease_cause
Virginiamycin
Microbiology
Bacterial Proteins
Mechanisms of Resistance
Streptococcal Infections
medicine
Humans
Pharmacology (medical)
Lincosamides
Antibacterial agent
Pharmacology
Genetics
Electrophoresis, Agar Gel
biology
Peptostreptococcus
Reverse Transcriptase Polymerase Chain Reaction
Genetic transfer
Drug Resistance, Microbial
Methyltransferases
biology.organism_classification
Streptococcaceae
Anti-Bacterial Agents
Infectious Diseases
Genes, Bacterial
Conjugation, Genetic
Macrolides
medicine.drug
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....da7af60664df8a84ac486d907cc25228