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Open software platform for automated analysis of paper-based microfluidic devices
- Source :
- Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020), Scientific Reports
- Publication Year :
- 2020
- Publisher :
- Nature Portfolio, 2020.
-
Abstract
- Development of paper-based microfluidic devices that perform colorimetric measurements requires quantitative image analysis. Because the design geometries of paper-based microfluidic devices are not standardized, conventional methods for performing batch measurements of regularly spaced areas of signal intensity, such as those for well plates, cannot be used to quantify signal from most of these devices. To streamline the device development process, we have developed an open-source program called ColorScan that can automatically recognize and measure signal-containing zones from images of devices, regardless of output zone geometry or spatial arrangement. This program, which measures color intensity with the same accuracy as standard manual approaches, can rapidly process scanned device images, simultaneously measure identified output zones, and effectively manage measurement results to eliminate requirements for time-consuming and user-dependent image processing procedures.
- Subjects :
- Computer science
Science
Microfluidics
Image processing
02 engineering and technology
01 natural sciences
Signal
Article
Imaging studies
Medical and clinical diagnostics
Measure (data warehouse)
Multidisciplinary
Lab-on-a-chip
business.industry
010401 analytical chemistry
Color intensity
Process (computing)
Bioanalytical chemistry
Paper based
021001 nanoscience & nanotechnology
0104 chemical sciences
Open software
Medicine
0210 nano-technology
business
Computer hardware
Subjects
Details
- Language :
- English
- ISSN :
- 20452322
- Volume :
- 10
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Scientific Reports
- Accession number :
- edsair.doi.dedup.....da6fa3eff60c30df546198ce955fe9ca