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Diagnosis and Management of Pain in Parkinson's Disease: A New Approach
- Source :
- Drugsaging. 38(7)
- Publication Year :
- 2021
-
Abstract
- Pain is a frequent and disabling non-motor feature of Parkinson's disease (PD). The recently proposed PD Pain Classification System (PD-PCS) allows for an association of pain with PD to be determined before being allocated to the main pain mechanism (i.e. nociceptive, neuropathic, and nociplastic). In this article, previous studies on treatments for pain in PD are summarized according to the pain mechanisms. A mechanistic approach to treatment is discussed. We suggest that the first step should be optimizing dopaminergic therapy before other therapy is started. When these treatments remain unsuccessful, further causes of pain must be considered. The role of drugs, invasive treatments, and physiotherapeutic interventions are discussed with a focus on older PD patients and considering polypharmacy, altered pharmacokinetics, and comorbidities.
- Subjects :
- Polypharmacy
medicine.medical_specialty
Parkinson's disease
Invasive treatments
business.industry
Pharmacology toxicology
Psychological intervention
Pain
Parkinson Disease
Disease
medicine.disease
Nociception
Physical medicine and rehabilitation
Pharmacotherapy
medicine
Humans
Pharmacology (medical)
Geriatrics and Gerontology
business
Pain Measurement
Subjects
Details
- ISSN :
- 11791969
- Volume :
- 38
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- Drugsaging
- Accession number :
- edsair.doi.dedup.....da6be277db984ed212457233c072eea0