Anaphylactic reaction to chlorpropamide

The total incidence of untoward reactions to chlorpropamideis about 6% (Sayers and Travis, 1965). Gastrointestinal symp-toms, skin reactions, and blood dyscrasias constitute the majorgroups (Stein et al., 1964; Dinsdale et al., 1968; Aecker andHynes, 1969; Norman et al., 1970). The anaphylactic reactionto chlorpropamide as described in the following case has