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The relationship between isolated pes equinovarus and aneuploidies and perinatal outcomes: Results of a tertiary center
- Source :
- Turkish Journal of Obstetrics and Gynecology, Turkish Journal of Obstetrics and Gynecology, Vol 17, Iss 4, Pp 270-277 (2020)
- Publication Year :
- 2020
- Publisher :
- Galenos Publishing, 2020.
-
Abstract
- Objective: Congenital pes equinovarus (PEV) is the most common congenital deformity of the foot, characterized by plantar flexion with a frequency of 0.2-0.3%. It can be diagnosed from the 12th week of pregnancy. Non-isolated cases tend to be syndromic and complex. We aimed to evaluate the results of perinatally diagnosed isolated PEV. Materials and Methods: This was a retrospective cohort study conducted between March 2015-March 2020. Women who presented for fetal anomaly screening or were referred due to any suspected fetal anomaly were subjected to detailed fetal anomaly scans and checked for the presence of PEV. Karyotype analysis was discussed for patients with PEV. Pregnancy termination was recommended for those with chromosomal/life-threatening anomalies. The diagnosis was confirmed by postnatal examination/autopsy. Postnatal diagnosis was accepted as false-positive in those with no PEV. Results: One-hundred thirty-eight patients were found to have PEV, 41 (29.7%) of which were isolated. In the isolated group, the false-positive rate in the first trimester was significantly higher compared with the second trimester, 50%/15.3%, respectively (p
- Subjects :
- medicine.medical_specialty
Down syndrome
Clubfoot
diagnostic imaging
lcsh:Medicine
Autopsy
Pes equinovarus
Fetal anomaly
lcsh:Gynecology and obstetrics
03 medical and health sciences
0302 clinical medicine
medicine
030212 general & internal medicine
Clinical Investigation
lcsh:RG1-991
Pregnancy
030219 obstetrics & reproductive medicine
Obstetrics
business.industry
lcsh:R
Obstetrics and Gynecology
Retrospective cohort study
karyotyping
medicine.disease
Trisomy
business
Subjects
Details
- Language :
- English
- ISSN :
- 21499330 and 21499322
- Volume :
- 17
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Turkish Journal of Obstetrics and Gynecology
- Accession number :
- edsair.doi.dedup.....da1e47be3c4c496d8dc4bfbe898c06fd