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Multiline treatment of advanced squamous cell carcinoma of the lung: A case report and review of the literature
- Source :
- World Journal of Clinical Cases
- Publication Year :
- 2019
- Publisher :
- Baishideng Publishing Group Inc, 2019.
-
Abstract
- BACKGROUND Squamous cell carcinoma (SCC) is one the most common subtypes of non-small cell lung cancer, yet the treatment options for it remain limited. Here, we report a case of advanced SCC and review the related literature focusing on the multiline therapy method. CASE SUMMARY We report the case of a 45-year-old man with advanced SCC who was deemed inoperable at the time of advanced SCC diagnosis. The patient had been referred to our hospital in April 2013 with complaints of a stuffy feeling in the chest, dyspnea, and pain in the right shoulder lasting for 1 mo. Physical examination found no obvious abnormalities, except for lower breath sound in the right lower lung. Laboratory data were within normal limits. Immunohistochemistry analysis of the tumor tissue showed CK5/6 (+), p63 (+), CD56 (+), and Ki-67 (+, approximately 30%), and genetic testing detected no EGFR mutation. He received a multiline treatment that included chemotherapy, radiotherapy, targeted therapy, and antiangiogenic therapy. After more than 5-year comprehensive treatment, the patient remains alive. CONCLUSION This typical case highlights the importance of appropriate multiline therapy for those patients with advanced SCC.
- Subjects :
- Chemotherapy
Squamous-cell carcinoma of the lung
business.industry
medicine.medical_treatment
Antiangiogenic therapy
Case Report
Anaplastic lymphoma kinase-targeted therapy
General Medicine
respiratory system
Nab-paclitaxel
respiratory tract diseases
03 medical and health sciences
stomatognathic diseases
0302 clinical medicine
030220 oncology & carcinogenesis
Squamous cell carcinoma
medicine
Cancer research
030211 gastroenterology & hepatology
business
Subjects
Details
- Language :
- English
- ISSN :
- 23078960
- Volume :
- 7
- Issue :
- 14
- Database :
- OpenAIRE
- Journal :
- World Journal of Clinical Cases
- Accession number :
- edsair.doi.dedup.....d99e0e2bc7e663190f43b24964886b78