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Endemic Pemphigus Foliaceus in Venezuela: Report of Two Children
- Source :
- Pediatric Dermatology. 23:132-135
- Publication Year :
- 2006
- Publisher :
- Wiley, 2006.
-
Abstract
- Two native Yanomami children from the Venezuelan Amazonia with erythroderma were hospitalized on our service. Clinical, histologic, and immunofluorescence studies diagnosed endemic pemphigus foliaceous. Human leukocyte antigen class II showed DRB1*04 subtype *0411, which has not been previously associated with this disease. However, it shares a common epitope with all the human leukocyte antigen DRB1 alleles that have been involved in this disease among Brazilian populations. Although this condition is endemic in Brazil, our patients are the first two reported in Venezuela.
- Subjects :
- Male
medicine.medical_specialty
Adolescent
Erythroderma
Dermatology
Disease
Human leukocyte antigen
Immunofluorescence
Epitope
Diagnosis, Differential
medicine
Humans
Child
Autoimmune disease
medicine.diagnostic_test
business.industry
Chloroquine
Venezuela
medicine.disease
Pemphigus
El Niño
Pediatrics, Perinatology and Child Health
Immunology
Prednisone
Female
business
Subjects
Details
- ISSN :
- 15251470 and 07368046
- Volume :
- 23
- Database :
- OpenAIRE
- Journal :
- Pediatric Dermatology
- Accession number :
- edsair.doi.dedup.....d98c1c9b13839f80cf47c66b5a38fc24
- Full Text :
- https://doi.org/10.1111/j.1525-1470.2006.00197.x