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Supplementation of prebiotics to a whey-based beverage reduces the risk of hypercholesterolaemia in rats
- Source :
- International Dairy Journal, 48, 80-84. Elsevier BV
- Publication Year :
- 2015
- Publisher :
- Elsevier BV, 2015.
-
Abstract
- Fructooligosaccharide-supplemented whey drinks may have potential as an interventional strategy for lowering cholesterol and triglyceride levels in dyslipidaemic conditions. A bioefficacy study was conducted in normal, hypercholesterolaemic and hyperglycaemic Sprague Dawley rats, running two consecutive trials for validity of results. Control drink (T 0 ), whey drink (T 1 ) and whey drink supplemented with 1.5% fructooligosaccharides (T 4 ), were given to each group. The functional drink caused a significant reduction in serum total cholesterol, low density lipoprotein (LDL) and triglycerides, and an increase in high density lipoprotein. The greatest decline in total cholesterol was induced by T 4 (10.9% and 12.0% in hypercholesterolaemic rats and 7.0% and 7.7% in hyperglycaemic rats, for trials 1 and 2, respectively). The decrease in total cholesterol by T 4 was mainly due to a pronounced decrease in LDL cholesterol (14.7% and 16.1% in hypercholesterolaemic rats and 7.4% and 8.1% in hyperglycaemic rats for trials 1 and 2, respectively).
Details
- Language :
- English
- ISSN :
- 09586946
- Volume :
- 48
- Database :
- OpenAIRE
- Journal :
- International Dairy Journal
- Accession number :
- edsair.doi.dedup.....d98bce88e90230c8cd0cba369c4d20f7