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Propofol Reduces Microelectrode-Recording Artefacts caused by Parkinsonian Tremor during Deep Brain Stimulation
- Source :
- Journal of Neuroanaesthesiology and Critical Care, Vol 05, Iss 01, Pp 21-25 (2018)
- Publication Year :
- 2018
- Publisher :
- Thieme Medical and Scientific Publishers Pvt. Ltd., 2018.
-
Abstract
- A 51-year-old male with medically refractory Parkinson's disease was scheduled for bilateral deep brain stimulation (DBS). During microelectrode recordings (MERs) of right side DBS, the patient developed severe sustained whole-body tremors causing severe artefacts in MER. The right side DBS electrode was inserted with suboptimal MER. For the creation of left burr hole, propofol infusion at a rate of 20 μg/kg/min, was used and soon after, all tremor activity ceased. Propofol infusion was continued during left side MER. With the absence of tremors, left subthalamic nucleus spike activity was better identified and neurological testing could take place. At 6 months after DBS, the patient’s symptoms had improved significantly without the need for levodopa.
- Subjects :
- Levodopa
Deep brain stimulation
parkinson’s disease
medicine.medical_treatment
a tremor effect
Critical Care and Intensive Care Medicine
lcsh:RD78.3-87.3
03 medical and health sciences
Microelectrode recording
0302 clinical medicine
Medicine
030212 general & internal medicine
propofol
business.industry
Left subthalamic nucleus
nervous system diseases
deep brain stimulation
Microelectrode
Anesthesiology and Pain Medicine
nervous system
lcsh:Anesthesiology
Anesthesia
Neurology (clinical)
business
Propofol
030217 neurology & neurosurgery
medicine.drug
Subjects
Details
- Language :
- English
- ISSN :
- 23480548
- Issue :
- 01
- Database :
- OpenAIRE
- Journal :
- Journal of Neuroanaesthesiology and Critical Care
- Accession number :
- edsair.doi.dedup.....d97a67d7a1ff063cec8539534bc4c9ce