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Langerhans cell histiocytosis in the oral and maxillofacial region: An update
- Source :
- Journal of oral pathologymedicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral PathologyREFERENCES. 50(6)
- Publication Year :
- 2021
-
Abstract
- Background Langerhans cell histiocytosis (LCH) is a rare disorder characterized by abnormal proliferation and infiltration of histiocytic cells. Methods This review focused on the main aspects associated with LCH. Results LCH can involve single or multiple organs and systems, with bone and skin being the most commonly affected sites. Regarding skeletal manifestations, the jawbones are involved in about 20%-30% of all cases. Such lesions may present as unilocular or multilocular images mainly affecting the posterior mandible. Oral soft tissue lesions may also occur, with the gingiva and hard palate being the most frequently affected sites. Conclusion The diagnosis and management of LCH are challenging, requiring a multidisciplinary approach, with dentists playing a central role since oral manifestations can be the first sign of the condition.
- Subjects :
- Cancer Research
Pathology
medicine.medical_specialty
Langerhans cell
Gingiva
Mandible
Pathology and Forensic Medicine
03 medical and health sciences
0302 clinical medicine
Letterer–Siwe disease
Langerhans cell histiocytosis
Eosinophilic granuloma
medicine
Hand–Schüller–Christian disease
Humans
Histiocyte
Skin
business.industry
030206 dentistry
medicine.disease
Histiocytosis
Histiocytosis, Langerhans-Cell
medicine.anatomical_structure
Otorhinolaryngology
030220 oncology & carcinogenesis
Periodontics
Hard palate
Oral Surgery
business
Subjects
Details
- ISSN :
- 16000714
- Volume :
- 50
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Journal of oral pathologymedicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral PathologyREFERENCES
- Accession number :
- edsair.doi.dedup.....d976c7fe59fbfc076f6bdfa9eb5ba0ca