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Neuroimaging-based biomarkers for pain
- Source :
- Pain Reports, PAIN Reports, Vol 4, Iss 4, p e751 (2019)
- Publication Year :
- 2019
-
Abstract
- Chronic pain is an endemic problem involving both peripheral and brain pathophysiology. Although biomarkers have revolutionized many areas of medicine, biomarkers for pain have remained controversial and relatively underdeveloped. With the realization that biomarkers can reveal pain-causing mechanisms of disease in brain circuits and in the periphery, this situation is poised to change. In particular, brain pathophysiology may be diagnosable with human brain imaging, particularly when imaging is combined with machine learning techniques designed to identify predictive measures embedded in complex data sets. In this review, we explicate the need for brain-based biomarkers for pain, some of their potential uses, and some of the most popular machine learning approaches that have been brought to bear. Then, we evaluate the current state of pain biomarkers developed with several commonly used methods, including structural magnetic resonance imaging, functional magnetic resonance imaging and electroencephalography. The field is in the early stages of biomarker development, but these complementary methodologies have already produced some encouraging predictive models that must be tested more extensively across laboratories and clinical populations.
- Subjects :
- Pain
Neuroimaging
Review
02 engineering and technology
Disease
Electroencephalography
01 natural sciences
Field (computer science)
lcsh:RD78.3-87.3
MVPA
0103 physical sciences
Machine learning
0202 electrical engineering, electronic engineering, information engineering
medicine
EEG
010306 general physics
medicine.diagnostic_test
business.industry
Chronic pain
medicine.disease
3. Good health
Anesthesiology and Pain Medicine
lcsh:Anesthesiology
Special Issue on Innovations and Controversies in Brain Imaging of Pain: Methods and Interpretations
Biomarker (medicine)
020201 artificial intelligence & image processing
Human brain imaging
Functional magnetic resonance imaging
business
Neuroscience
Biomarkers
MRI
Subjects
Details
- Language :
- English
- ISSN :
- 24712531
- Volume :
- 4
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Pain reports
- Accession number :
- edsair.doi.dedup.....d96cdf134ea04a29e906d2e9fa9919a3