Respiratory health status is impaired in UK HIV-positive adults with virologically suppressed HIV infection

Authors :: Santino Capocci
James W. Brown
Marc Lipman
CJ Smith
Jennifer McGowan
Margaret Johnson
Alison Rodger
L Sathia
D Ivens
Fiona C Lampe
H Chouial
R Shah
Source :: Brown, J, Mcgowan, J, Chouial, H, Capocci, S, Smith, C, Ivens, D, Johnson, M, Sathia, L, Shah, R, Lampe, F, Rodger, A & Lipman, M 2017, ' Respiratory health status is impaired in UK HIV-positive adults with virologically suppressed HIV infection ', HIV Medicine, vol. 18, no. 8 . https://doi.org/10.1111/hiv.12497
Publication Year :: 2017
Publisher :: Wiley, 2017.
Abstract: © 2017 British HIV Association.Objectives: We sought to evaluate whether people living with HIV (PLWH) using effective antiretroviral therapy (ART) have worse respiratory health status than similar HIV-negative individuals. Methods: We recruited 197 HIV-positive and 93 HIV-negative adults from HIV and sexual health clinics. They completed a questionnaire regarding risk factors for respiratory illness. Respiratory health status was assessed using the St George's Respiratory Questionnaire (SGRQ) and the Medical Research Council (MRC) breathlessness scale. Subjects underwent spirometry without bronchodilation. Results: PLWH had worse respiratory health status: the median SGRQ Total score was 12 [interquartile range (IQR) 6-25] in HIV-positive subjects vs. 6 (IQR 2-14) in HIV-negative subjects (P

Full Text Access

Tools