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Litholytic agents as an alternative treatment modality in patients with biliary dyspepsia
- Source :
- Medicine
- Publication Year :
- 2020
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2020.
-
Abstract
- Biliary dyspepsia presents as biliary colic in the absence of explanatory structural abnormalities. Causes include gallbladder dyskinesia, sphincter of Oddi dysfunction, biliary tract sensitivity, microscopic sludges, and duodenal hypersensitivity. However, no consensus treatment guideline exists for biliary dyspepsia. We investigated the effects of medical treatments on biliary dyspepsia. We retrospectively reviewed the electronic medical records of 414 patients who had biliary pain and underwent cholescintigraphy from 2008 to 2018. We enrolled patients who received litholytic agents and underwent follow-up scans after medical treatment. We divided the patients into the GD group (biliary dyspepsia with reduced gallbladder ejection fraction [GBEF]) and the NGD group (biliary dyspepsia with normal GBEF). We compared pre- and post-treatment GBEF and symptoms. Among 57 patients enrolled, 40 (70.2%) patients had significant GBEF improvement post-treatment, ranging from 34.4 ± 22.6% to 53.8 ± 26.8% (P
- Subjects :
- Adult
Male
medicine.medical_specialty
Observational Study
Biliary colic
Chenodeoxycholic Acid
Gastroenterology
gallbladder dyskinesia
03 medical and health sciences
0302 clinical medicine
Internal medicine
medicine
Bile
Humans
Gallbladder dyskinesia
030212 general & internal medicine
Dyspepsia
Retrospective Studies
medicine.diagnostic_test
business.industry
Medical record
Ursodeoxycholic Acid
Gallbladder
litholytic agent
Retrospective cohort study
General Medicine
Guideline
Middle Aged
medicine.disease
Cholescintigraphy
Biliary tract
030220 oncology & carcinogenesis
Sphincter of Oddi dysfunction
Female
biliary dyspepsia
medicine.symptom
business
Research Article
Subjects
Details
- ISSN :
- 15365964 and 00257974
- Volume :
- 99
- Database :
- OpenAIRE
- Journal :
- Medicine
- Accession number :
- edsair.doi.dedup.....d8ac5a30ffbbb379a15eae44630b295f