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Novel device-based acne treatments: comparison of a 1450-nm diode laser and microneedling radiofrequency on mild-to-moderate acne vulgaris and seborrhoea in Korean patients through a 20-week prospective, randomized, split-face study
- Source :
- Journal of the European Academy of Dermatology and Venereology. 32:639-644
- Publication Year :
- 2017
- Publisher :
- Wiley, 2017.
-
Abstract
- Background While device-based acne treatments are widely applied for patients not tolerating conventional medications, related controlled studies have been still limited. Recently, non-ablative 1450-nm diode laser (DL) and fractional microneedling radiofrequency (FMR) have been effectively used for acne, in addition to well-recognized dermal remodelling effects. Objective To compare the clinical course of acne treatment between DL and FMR. Methods Twenty-five Korean patients with mild-to-moderate facial acne completed treatments with DL and FMR through a 20-week, randomized split-face study. One randomly assigned half side of each patient's face received DL and the other side by FMR. Treatments were scheduled to receive three consecutive sessions at 4-week intervals. Objective assessments including revised Leeds grades, lesion counts, sebum output measurements, and patients' subjective satisfaction were investigated. Results Both DL and FMR demonstrated steady improvement of acne and seborrhoea during treatment sessions. While results between two devices were similar during treatment sessions, FMR was superior to DL in the 12-week follow-up. Patients' subjective assessments for seborrhoea improvement were similar between two devices, while those for acne, skin texture, and acne scars were more satisfactory for FMR. For safety profile, no significant difference was observed between two regimens, while mild postinflammatory hyperpigmentation was observed only in DL side. Conclusion Both DL and FMR demonstrated efficacies for acne and seborrhoea, with reasonable safety profile. FMR was more effective than DL for the long-term maintenance, and subjective assessments for texture and scar improvements. Therefore, a few sessions of these devices would be a viable option for acne treatments.
- Subjects :
- Adult
Male
medicine.medical_specialty
Adolescent
Dermatology
Severity of Illness Index
law.invention
Young Adult
030207 dermatology & venereal diseases
03 medical and health sciences
0302 clinical medicine
Patient satisfaction
Randomized controlled trial
law
Acne Vulgaris
Republic of Korea
Severity of illness
medicine
Humans
Prospective Studies
Prospective cohort study
Acne
business.industry
Seborrhoeic dermatitis
Acne treatment
medicine.disease
Dermatitis, Seborrheic
Sebum
Treatment Outcome
Infectious Diseases
Needles
Patient Satisfaction
030220 oncology & carcinogenesis
Female
Laser Therapy
medicine.symptom
business
Postinflammatory hyperpigmentation
Subjects
Details
- ISSN :
- 09269959
- Volume :
- 32
- Database :
- OpenAIRE
- Journal :
- Journal of the European Academy of Dermatology and Venereology
- Accession number :
- edsair.doi.dedup.....d89cb0c4d794b5e6c43c2c41ad4f5ffc