Genetic tracing reveals transcription factor Foxp3-dependent and Foxp3-independent functionality of peripherally induced Treg cells

Authors :: Joris van der Veeken
Clarissa Campbell
Yuri Pritykin
Michail Schizas
Jacob Verter
Wei Hu
Zhong-Min Wang
Fanny Matheis
Daniel Mucida
Louis-Marie Charbonnier
Talal A. Chatila
Alexander Y. Rudensky
Source :: Immunity. 55(7)
Publication Year :: 2021
Abstract: Regulatory T (Treg) cells expressing the transcription factor Foxp3 are an essential suppressive T cell lineage of dual origin: Foxp3 induction in thymocytes and mature CD4

Subjects :: Infectious Diseases
Thymocytes
Immunology
Immune Tolerance
Immunology and Allergy
Th17 Cells
Forkhead Transcription Factors
T-Lymphocytes, Regulatory

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