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Neuronal PET tracers for Alzheimer's disease

Authors :
Nivedita Singh
Deepak T. Nair
Justin Antony
Ashwini Prem Kumar
Source :
Biochemical and biophysical research communications. 587
Publication Year :
2021

Abstract

Advancements in brain imaging techniques have emerged as a significant tool in detecting Alzheimer's disease (AD) progression. The complicated cascade of AD progression can be detected using radio imaging, especially with Positron emission tomography (PET). The review focus on recently introduced investigational PET tracers targeting neurofibrillary tau aggregates found typically in AD. Herein, we also address the use of different PET tracers and the clinical implementation of established and newer generation tracers. This review also intends to discuss the importance of several PET radiotracers and challenges in PET imaging.

Details

ISSN :
10902104
Volume :
587
Database :
OpenAIRE
Journal :
Biochemical and biophysical research communications
Accession number :
edsair.doi.dedup.....d874f639611c3334a86efdf46964e0d4