Predicting Gene Function using Predictive Clustering Trees

In this chapter, we show how the predictive clustering tree framework can be used to predict the functions of genes. The gene function prediction task is an example of a hierarchical multi-label classification (HMC) task: genes may have multiple functions and these functions are organized in a hierarchy. The hierarchy of functions can be such that each function has at most one parent (tree structure) or such that functions may have multiple parents (DAG structure). © 2010 Springer Science+Business Media, LLC. ispartof: Inductive Databases and Constraint-based Data Mining pages:365-387 ispartof: pages:365-387 status: published