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Antisperm antibodies detected by mixed agglutination reaction and immunobead test are not associated with chronic inflammation and infection of the seminal tract
- Source :
- Andrologia. 40:227-234
- Publication Year :
- 2008
- Publisher :
- Hindawi Limited, 2008.
-
Abstract
- The association between chronic inflammatory/infectious diseases of the male reproductive tract and the presence of antisperm antibodies (ASA) in semen is still controversial. We compared the results of the mixed agglutinin reaction (MAR) test and immunobead test for detecting ASA type IgG and IgA in 133 patients attending our special outpatient department for andrological infections and evaluated the differences in the detection rate of ASA. Patients were divided into three groups: a study group that included 79 patients with symptomatic nonacute inflammatory/infectious diseases of the seminal tract, a control group (n = 44) and a third group of men with a history of successful vasectomy reversal (n = 10). The two tests correlated in a statistically significant manner for the detection of IgG and IgA in all groups. The overall positive detection rate of clinical significant levels of IgG and IgA was 2.5% and 1.3% (respectively) in the patients with inflammation/infection of the seminal tract. No statistical significant difference in the detection rate of ASA levels between the inflammatory/infectious group and the controls was detected. The results of the MAR test and immunobead test have a statistical significant correlation and their results provide evidence that there is no association between inflammatory/infectious diseases of the male reproductive tract and the presence of ASA in semen.
- Subjects :
- Adult
Male
Urology
Inflammation
Semen
Sensitivity and Specificity
Testicular Diseases
Male Reproductive Tract
Endocrinology
Agglutination Tests
Vasectomy
medicine
Humans
Outpatient clinic
Seminal tract
Immunoassay
biology
business.industry
Vasectomy reversal
Bacterial Infections
General Medicine
Middle Aged
Spermatozoa
Antibodies, Anti-Idiotypic
Immunoglobulin A
Agglutination (biology)
Case-Control Studies
Immunoglobulin G
Chronic Disease
Immunology
biology.protein
medicine.symptom
Antibody
business
Subjects
Details
- ISSN :
- 14390272 and 03034569
- Volume :
- 40
- Database :
- OpenAIRE
- Journal :
- Andrologia
- Accession number :
- edsair.doi.dedup.....d85917084d10d06eb920c23571b320f0