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Adult-onset type 1 diabetes: Predictors of glycaemic control

Authors :
Martin Ridderstråle
Dan Hesse
Louise Boysen
Source :
Endocrinology, Diabetes & Metabolism
Publication Year :
2018
Publisher :
Wiley, 2018.

Abstract

Summary Aims Knowledge about adult‐onset (AO) type 1 diabetes remains insufficient. We sought to characterize the initial 5 years of AO type 1 diabetes and hypothesized that initial factors predictive of subsequent glycaemic control might exist. Materials and methods A retrospective cohort study based on electronic medical records of 280 subjects with newly diagnosed AO type 1 diabetes (>18 years of age, excluding secondary and latent autoimmune diabetes) with available data for the initial 5‐year treatment. Results Characteristics at diagnosis: 61% men, mean age 37 ± 12 years, BMI 23 ± 3.3 (kg/m2), systolic/diastolic blood pressure: 123 ± 15/76 ± 9 mm Hg and LDL cholesterol: 2.9 ± 0.9 mmol/L. HbA1c decreased from 106 mmol/mol (11.8%) at diagnosis to 52 mmol/mol (6.9%) at 6 months and then increased gradually to 67 mmol/mol (8.3%) after 5 years. Strict glycaemic control (

Details

ISSN :
23989238
Volume :
1
Database :
OpenAIRE
Journal :
Endocrinology, Diabetes & Metabolism
Accession number :
edsair.doi.dedup.....d84484ab1f234b9c92a871fe6efcf9bb
Full Text :
https://doi.org/10.1002/edm2.38