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Pseudogene.org: a comprehensive database and comparison platform for pseudogene annotation
- Source :
- Nucleic Acids Research
- Publication Year :
- 2006
- Publisher :
- Oxford University Press, 2006.
-
Abstract
- The Pseudogene.org knowledgebase serves as a comprehensive repository for pseudogene annotation. The definition of a pseudogene varies within the literature, resulting in significantly different approaches to the problem of identification. Consequently, it is difficult to maintain a consistent collection of pseudogenes in detail necessary for their effective use. Our database is designed to address this issue. It integrates a variety of heterogeneous resources and supports a subset structure that highlights specific groups of pseudogenes that are of interest to the research community. Tools are provided for the comparison of sets and the creation of layered set unions, enabling researchers to derive a current 'consensus' set of pseudogenes. Additional features include versatile search, the capacity for robust interaction with other databases, the ability to reconstruct older versions of the database (accounting for changing genome builds) and an underlying object-oriented interface designed for researchers with a minimal knowledge of programming. At the present time, the database contains more than 100,000 pseudogenes spanning 64 prokaryote and 11 eukaryote genomes, including a collection of human annotations compiled from 16 sources.
- Subjects :
- Interface (Java)
Pseudogene
Biology
computer.software_genre
Genome
Set (abstract data type)
03 medical and health sciences
Annotation
User-Computer Interface
0302 clinical medicine
Databases, Genetic
Genetics
Humans
030304 developmental biology
Structure (mathematical logic)
0303 health sciences
Internet
Database
business.industry
Articles
Identification (information)
030220 oncology & carcinogenesis
The Internet
business
computer
Pseudogenes
Software
Subjects
Details
- Language :
- English
- ISSN :
- 13624962 and 03051048
- Volume :
- 35
- Database :
- OpenAIRE
- Journal :
- Nucleic Acids Research
- Accession number :
- edsair.doi.dedup.....d8315ebcc46da2206017914c5ca606b6