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High-Dose-Rate 192Ir Brachytherapy Dose Verification: A Phantom Study
- Source :
- Iranian Journal of Cancer Prevention
- Publication Year :
- 2015
- Publisher :
- Briefland, 2015.
-
Abstract
- Background: The high-dose-rate (HDR) brachytherapy might be an effective tool for palliation of dysphagia. Because of some concerns about adverse effects due to absorbed radiation dose, it is important to estimate absorbed dose in risky organs during this treatment. Objectives: This study aimed to measure the absorbed dose in the parotid, thyroid, and submandibular gland, eye, trachea, spinal cord, and manubrium of sternum in brachytherapy in an anthropomorphic phantom. Materials and Methods: To measure radiation dose, eye, parotid, thyroid, and submandibular gland, spine, and sternum, an anthropomorphic phantom was considered with applicators to set thermoluminescence dosimeters (TLDs). A specific target volume of about 23 cm3 in the upper thoracic esophagus was considered as target, and phantom planned computed tomography (CT) for HDR brachytherapy, then with a micro-Selectron HDR (192Ir) remote after-loading unit. Results: Absorbed doses were measured with calibrated TLDs and were expressed in centi-Gray (cGy). In regions far from target (≥ 16 cm) such as submandibular, parotid and thyroid glands, mean measured dose ranged from 1.65 to 5.5 cGy. In closer regions (≤ 16 cm), the absorbed dose might be as high as 113 cGy. Conclusions: Our study showed similar depth and surface doses; in closer regions, the surface and depth doses differed significantly due to the role of primary radiation that had imposed a high-dose gradient and difference between the plan and measurement, which was more severe because of simplifications in tissue inhomogeneity, considered in TPS relative to phantom.
- Subjects :
- Cancer Research
Esophageal Cancer
Phantom
business.industry
medicine.medical_treatment
Brachytherapy
digestive, oral, and skin physiology
Imaging phantom
Radiation therapy
stomatognathic system
Oncology
Absorbed dose
Genetics
medicine
Dose verification
Dose rate
Nuclear medicine
business
Absorbed Radiation Dose
Genetics (clinical)
Research Article
Subjects
Details
- ISSN :
- 20082401 and 20082398
- Volume :
- 8
- Database :
- OpenAIRE
- Journal :
- Iranian Journal of Cancer Prevention
- Accession number :
- edsair.doi.dedup.....d82030694f0f9ee4569f516f4b9d81bf