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Severity Scores in Children With Acute Pancreatitis
- Source :
- Journal of Pediatric Gastroenterology & Nutrition. 55:266-267
- Publication Year :
- 2012
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2012.
-
Abstract
- Severity scores are used to predict the outcome of acute pancreatitis (AP). Several scores are used in adult patients, but none has been thoroughly validated for specific use in paediatric patients. We retrospectively collected data from 48 children with AP (13 severe and 35 mild). The main causes were trauma (23%), idiopathic (23%), lithiasis (12.5%), and virus (10.5%). We evaluated 3 clinical scores (Ranson, Glasgow modified, and DeBanto) and Balthazar computed tomography severity index. The clinical scores had a good specificity (approximately 85%) but a low sensitivity (approximately 55%) in predicting the severity of paediatric AP. The radiological score is better (sensitivity 80%, specificity 86%). The area under the receiver operator characteristic curve was 0.699 (95% CI 0.508%-0.891%, P = 0.054) for the DeBanto score, 0.846 (95% CI 0.69%-1%, P = 0.001) for the Ranson score, and 0.774 (95% CI 0.584%-0.964%, P = 0.008) for the Glasgow and 0.898 (95% CI 0.73%-1%, P = 0.011) for the Balthazar computed tomography severity index score. In our paediatric cohort, the severity of AP was best predicted by Balthazar computed tomography-based scoring scale. Our results confirm previously reported low sensitivity of adult-based clinical scoring scales.
- Subjects :
- Male
medicine.medical_specialty
Computed tomography
Lithiasis
Sensitivity and Specificity
Severity of Illness Index
Gastroenterology
Internal medicine
Severity of illness
medicine
Humans
Child
Retrospective Studies
Paediatric patients
Adult patients
medicine.diagnostic_test
Receiver operating characteristic
business.industry
medicine.disease
Index score
Pancreatitis
ROC Curve
Virus Diseases
Area Under Curve
Acute Disease
Pediatrics, Perinatology and Child Health
Cohort
Wounds and Injuries
Acute pancreatitis
Female
Tomography, X-Ray Computed
business
Subjects
Details
- ISSN :
- 02772116
- Volume :
- 55
- Database :
- OpenAIRE
- Journal :
- Journal of Pediatric Gastroenterology & Nutrition
- Accession number :
- edsair.doi.dedup.....d7c0ff50f86be2f29f843707a84696cb