qnrA in CTX-M-Producing Escherichia coli Isolates from France▿

By PCR, we screened for qnr genes 112 clinical isolates of extended-spectrum β-lactamase-producing Escherichia coli collected from hospitals in France during 2004. For the first time, 7.7% of CTX-M-producing E. coli isolates presented a plasmid-mediated resistance to quinolones. All strains harbored a qnrA gene located on a sul1 -type class 1 integron with similar structure to the In 36 integron.