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Role of cervical cytology in surveillance after radical trachelectomy for cervical cancer
- Source :
- Gynecologic Oncology. 142:283-285
- Publication Year :
- 2016
- Publisher :
- Elsevier BV, 2016.
-
Abstract
- There are currently no standard guidelines on the use of Papanicolaou (Pap) tests for surveillance after radical trachelectomy for cervical cancer. The goal of this study was to determine the usefulness of Pap tests in routine surveillance after radical trachelectomy for cervical cancer.Cervical cancer patients who underwent radical trachelectomy from January 2004 through October 2015 and subsequently had at least one Pap test were retrospectively identified. Demographic and clinical characteristics were described and compared between patients with and without at least one abnormal Pap test. The Kaplan-Meier method was used to estimate time to first abnormal Pap test.Forty-one patients met inclusion criteria. Of these, 30 (73%) had at least one year in which more than one Pap test per year was obtained. Twenty-four (59%) had at least one abnormal Pap test. Of 238 total Pap tests collected, 44 (18%) were abnormal. The most common abnormality was ASCUS (52%, n=23). Other findings included LSIL (20%, n=9), HSIL (2%, n=1), and AGUS (25%, n=11). Median time from radical trachelectomy to first abnormal Pap test was 17.2months (range, 11.8-86.3). No patient had disease recurrence. Surgery type (laparoscopic, open, or robotic), trachelectomy specimen size, histology, device for stenosis prevention (pediatric Foley catheter or Smit Sleeve), and cerclage placement were not significant predictors of an abnormal Pap test.The rate of abnormal Pap tests after radical trachelectomy is high; however, the clinical significance of such abnormalities appears limited. The routine use of cervical cytology as surveillance after radical trachelectomy does not appear to substantially impact management decisions.
- Subjects :
- medicine.medical_specialty
Trachelectomy
Decision Making
Uterine Cervical Neoplasms
Papanicolaou stain
Article
03 medical and health sciences
0302 clinical medicine
medicine
Humans
Pap test
Neoplasm Staging
Retrospective Studies
Cervical cancer
Gynecology
030219 obstetrics & reproductive medicine
medicine.diagnostic_test
business.industry
Obstetrics and Gynecology
Cervical cytology
medicine.disease
female genital diseases and pregnancy complications
Oncology
030220 oncology & carcinogenesis
Female
business
Papanicolaou Test
Subjects
Details
- ISSN :
- 00908258
- Volume :
- 142
- Database :
- OpenAIRE
- Journal :
- Gynecologic Oncology
- Accession number :
- edsair.doi.dedup.....d78d1d4bf232fea056b04d788a9a0b77