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Optimizing NBE PK/PD assays using the Gyrolab Affinity Software; conveniently within the bioanalyst's existing workflow
- Source :
- Bioanalysis. 10:397-406
- Publication Year :
- 2018
- Publisher :
- Future Science Ltd, 2018.
-
Abstract
- Aim: The fully automated microfluidics-based Gyrolab is a popular instrument for the bioanalysis of protein therapeutics; requiring minimal sample and reagent volumes. Gyros offers affinity software for determining binding affinity in solution using a high-throughput method and miniaturized reactions. Results: Using this affinity software, multiple CTGF-targeting reagents were characterized on the Gyrolab after
- Subjects :
- Bioanalysis
Clinical Biochemistry
030226 pharmacology & pharmacy
01 natural sciences
Workflow
Analytical Chemistry
03 medical and health sciences
0302 clinical medicine
Software
Humans
General Pharmacology, Toxicology and Pharmaceutics
PK/PD models
Binding affinities
Immunoassay
Chromatography
Protein therapeutics
Chemistry
business.industry
010401 analytical chemistry
Antibodies, Monoclonal
General Medicine
0104 chemical sciences
Medical Laboratory Technology
Fully automated
Biological Assay
business
Automated immunoassay
Subjects
Details
- ISSN :
- 17576199 and 17576180
- Volume :
- 10
- Database :
- OpenAIRE
- Journal :
- Bioanalysis
- Accession number :
- edsair.doi.dedup.....d754d041ec368ad7e12747657cf77d90