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Optimizing NBE PK/PD assays using the Gyrolab Affinity Software; conveniently within the bioanalyst's existing workflow

Authors :
Erica Waltz
Rachel Kroe-Barrett
Tammy Bigwarfe
Sarah Low
John Miglietta
Hua Li
Cynthia Hess Kenny
Maria Myzithras
Jennifer Ahlberg
Irina Rybina
Source :
Bioanalysis. 10:397-406
Publication Year :
2018
Publisher :
Future Science Ltd, 2018.

Abstract

Aim: The fully automated microfluidics-based Gyrolab is a popular instrument for the bioanalysis of protein therapeutics; requiring minimal sample and reagent volumes. Gyros offers affinity software for determining binding affinity in solution using a high-throughput method and miniaturized reactions. Results: Using this affinity software, multiple CTGF-targeting reagents were characterized on the Gyrolab after

Details

ISSN :
17576199 and 17576180
Volume :
10
Database :
OpenAIRE
Journal :
Bioanalysis
Accession number :
edsair.doi.dedup.....d754d041ec368ad7e12747657cf77d90