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Growth-Inhibitory Activities of Benzofuran and Chromene Derivatives toward Tenebrio molitor
- Source :
- Journal of Natural Products. 61:1209-1211
- Publication Year :
- 1998
- Publisher :
- American Chemical Society (ACS), 1998.
-
Abstract
- Growth-inhibitory activities of selected natural benzofurans (4-9), trans-cinnamic acid derivatives (10-13), chromene compounds (14 and 16), and some semisynthetic derivatives were determined in last instar larvae of Tenebrio molitor via topical administration in Me2CO. The most inhibitory of the tested compounds were 3-gamma, gamma-dimethylallyl-p-coumaric acid (10) and the benzofuran derivative 12-(p-cumaroyloxy)-tremetone (5), the former compound acting on the pupae and the latter on the last instar larvae. Several developmental deficiencies were observed, and some structure-activity relationships are discussed.
- Subjects :
- Pharmacology
Insecticides
Stereochemistry
Organic Chemistry
Pharmaceutical Science
Growth inhibitory
Plants
Growth Inhibitors
Cinnamic acid
Analytical Chemistry
chemistry.chemical_compound
Complementary and alternative medicine
chemistry
Drug Discovery
Insect growth regulator
Animals
Molecular Medicine
Instar
Organic chemistry
Phenols
Chromans
Benzofuran
Tenebrio
Benzofurans
Subjects
Details
- ISSN :
- 15206025 and 01633864
- Volume :
- 61
- Database :
- OpenAIRE
- Journal :
- Journal of Natural Products
- Accession number :
- edsair.doi.dedup.....d710ea2d65f470a9d0bcc733225e9102