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Bisphenol A in human saliva and urine before and after treatment with dental polymer-based restorative materials
- Source :
- European Journal of Oral Sciences
- Publication Year :
- 2019
-
Abstract
- The aim of this study was to quantify bisphenol A (BPA) concentrations in saliva and urine before and after treatment with dental polymer-based restorative materials to assess if placement of this material is associated with increased BPA levels in saliva and urine. Twenty individuals in need of at least one dental restoration with polymer-based restorative material were included in this study. The participants were instructed to abstain from eating, drinking, and brushing their teeth for at least 10 h prior to sampling. Saliva and urine were collected before and 10 min (saliva only), 1 h, 24 h, and 1 wk after treatment. Samples were stored at 80°C before analyses. BPA in saliva and urine was determined with liquid chromatography/mass spectrometry. Linear mixed effects regression models were used for statistical analyses. There was a statistically significant increase of salivary BPA concentration directly after placement of the dental polymer-based restorations. Following placement, the concentration of BPA decreased exponentially with time. One week after treatment the BPA level in saliva was only marginally higher than before treatment. In urine, no statistically significant change of the BPA concentration was detected after treatment. publishedVersion
- Subjects :
- Male
Bisphenol A
Saliva
endocrine system
Polymers
resin‐based material
medicine.medical_treatment
0206 medical engineering
Dentistry
02 engineering and technology
Urine
composite filling
Mixed effects regression
exposure to BPA
03 medical and health sciences
chemistry.chemical_compound
Dental Materials
0302 clinical medicine
stomatognathic system
Phenols
Statistical analyses
Medicine
Humans
Benzhydryl Compounds
General Dentistry
saliva
business.industry
urogenital system
030206 dentistry
Original Articles
020601 biomedical engineering
urine
stomatognathic diseases
chemistry
Restorative material
Female
Original Article
business
Dental restoration
After treatment
hormones, hormone substitutes, and hormone antagonists
Subjects
Details
- ISSN :
- 16000722
- Volume :
- 127
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- European journal of oral sciences
- Accession number :
- edsair.doi.dedup.....d70e509133f763820afe363a9aaab345