Design and synthesis of new polyphosphorylated upper-rim modified calix[4]arenes as potential and selective chelating agents of uranyl ion

Authors :: Evelyne Migianu-Griffoni
Marc Lecouvey
Frédéric Taran
Delphine Lecerclé
Cyrille Mbemba
Ramon Burgada
Chimie, Structures et Propriétés de Biomatériaux et d'Agents Thérapeutiques (CSPBAT)
Université Paris 13 (UP13)-Institut Galilée-Université Sorbonne Paris Cité (USPC)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)
Source :: Tetrahedron, Tetrahedron, Elsevier, 2009, 65 (7), pp.1517-1523. ⟨10.1016/j.tet.2008.11.076⟩
Publication Year :: 2009
Publisher :: HAL CCSD, 2009.
Abstract: 1 - Article; New upper-rim polyphosphorylated calix[4]arenes were designed for decorporation of uranium in case of nuclear contamination. A ligand system containing four preorganized 1-hydroxymethylene-1,1-bisphosphonic acid moieties anchored onto a calix[4]arene platform has been developed. Three calix[4]arene-bisphosphonates were efficiently prepared in multi-step syntheses with a variable carbon chain length between the bisphosphonate and the calix[4]arene. Affinity constants towards uranyl ion were determined and compared with those of bis(HEDP) and tris(HEDP) phosphonates, known as efficient ligands for uranyl.

Language :: English
ISSN :: 00404020
Database :: OpenAIRE
Journal :: Tetrahedron, Tetrahedron, Elsevier, 2009, 65 (7), pp.1517-1523. ⟨10.1016/j.tet.2008.11.076⟩
Accession number :: edsair.doi.dedup.....d6fcace3d59d4cf88d7f7c1281b84e54
Full Text :: https://doi.org/10.1016/j.tet.2008.11.076⟩

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