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Primary leptomeningeal T-cell lymphoblastic lymphoma: a rare cause of chronic meningitis

Authors :
Sudheer Arava
Arunmozhimaran Elavarasi
Rohit Bhatia
Lalit Kumar
Source :
BMJ Case Rep
Publication Year :
2020
Publisher :
BMJ, 2020.

Abstract

Primary leptomeningeal lymphomatosis is a rare disease with only a few hundred cases reported. We present a patient with a relatively short history of 25 days of headache followed by diplopia who was found to have primary leptomeningeal T-cell lymphoma without evidence of systemic lymphoma. The patient responded well to chemotherapy along with intrathecal medication and cranial irradiation and returned to a completely normal state of health. Not all chronic meningitis is due to infection or self-limiting inflammatory causes. It is important to consider lymphoma as a differential even in the absence of constitutional features such as loss of weight, appetite, night sweats, lymphadenopathy or hepatosplenomegaly. T-cell lymphoma with only Central Nervous system (CNS) involvement is a rare cause of chronic meningitis, which is eminently amenable to treatment and is fatal if missed.

Details

ISSN :
1757790X
Volume :
13
Database :
OpenAIRE
Journal :
BMJ Case Reports
Accession number :
edsair.doi.dedup.....d6ec36e5177a33c4760ae7587e3f350a
Full Text :
https://doi.org/10.1136/bcr-2020-236491