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Retrospective study of proliferative urethritis in dogs: Clinical presentation and outcome using various treatment modalities in 11 dogs
- Source :
- Journal of Veterinary Internal Medicine
- Publication Year :
- 2020
- Publisher :
- Wiley, 2020.
-
Abstract
- Background Proliferative urethritis (PU) is an uncommon inflammatory and infiltrative disease of the urethra in female dogs, often associated with urinary tract infection (UTI). It typically presents with evidence of urethral obstruction (UO). Objectives Identify clinical features in dogs with PU and determine outcome after different treatment modalities. Animals Eleven client-owned dogs. Methods Medical records of dogs with histopathologic diagnosis of PU from 2011 to 2020 were retrospectively evaluated, including information on clinical pathology, imaging, and histopathology. Outcomes of various treatment modalities were recorded and compared. Long-term urethral patency (>6 months) was considered treatment success. Results All dogs were female and presented with UO. Eight (73%) had a history of UTI. Ten of 11 survived to discharge and were used for long-term data collection. Seven of 10 (70%) were treated using an effacement procedure (balloon dilatation [BD], stent, or both) and 6/7 (86%) achieved long-term urethral patency (>6 months). Seven of 10 had UO recurrence after their first procedure, including 3/3 (100%) that did not have effacement and 4/7 that did (57%), at a median of 101 days and 687 days, respectively. After effacement, the duration of patency was longer for those treated using a stent than BD alone (median, 843 days and 452 days, respectively). Conclusions and clinical importance Proliferative urethritis is a recurrent disease often associated with UTI. The best outcome of long-term urethral patency occurred after lesion effacement, either by BD or stenting. Future prospective studies should determine the impact of immunosuppressive treatment.
- Subjects :
- medicine.medical_specialty
Urethral Obstruction
040301 veterinary sciences
medicine.medical_treatment
Urinary system
Standard Article
030204 cardiovascular system & hematology
0403 veterinary science
03 medical and health sciences
Dogs
0302 clinical medicine
medicine
Nephrology/Urology
Animals
Urethritis
Dog Diseases
Prospective Studies
Prospective cohort study
Retrospective Studies
General Veterinary
Clinical pathology
business.industry
Stent
Retrospective cohort study
04 agricultural and veterinary sciences
medicine.disease
Standard Articles
urethral patency
Surgery
Treatment Outcome
Urethra
medicine.anatomical_structure
proliferative urethritis
Female
Histopathology
SMALL ANIMAL
effacement
business
Subjects
Details
- ISSN :
- 19391676 and 08916640
- Volume :
- 35
- Database :
- OpenAIRE
- Journal :
- Journal of Veterinary Internal Medicine
- Accession number :
- edsair.doi.dedup.....d6d74a6ea4b2d7b93a15503230b602d1