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Immune cell profiling in Gleason 9 prostate cancer patients treated with brachytherapy versus external beam radiotherapy: An exploratory study

Authors :
X. Huang
H. Wang
Lucas C. Mendez
Aruz Mesci
Hans Chung
Stanley K. Liu
Gerard Morton
Danny Vesprini
Stephanie Chan
Andrew Loblaw
Michelle R Downes
Source :
Radiotherapy and Oncology. 155:80-85
Publication Year :
2021
Publisher :
Elsevier BV, 2021.

Abstract

This exploratory study evaluates immunological changes in high-risk Gleason 9 prostate cancer patients treated with EBRT+BT compared to EBRT alone. Notably, BT demonstrates the potential to elicit a T cell response which may support further investigation using circulating immune cells as predictive and prognostic biomarkers for radiotherapy response.

Details

ISSN :
01678140
Volume :
155
Database :
OpenAIRE
Journal :
Radiotherapy and Oncology
Accession number :
edsair.doi.dedup.....d6a3c72eafecfd7dff05a83c9328808b
Full Text :
https://doi.org/10.1016/j.radonc.2020.10.029