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Neutral desorption extractive electrospray ionization mass spectrometry for fast screening sunscreen agents in cream cosmetic products
- Source :
- Talanta. 85:1665-1671
- Publication Year :
- 2011
- Publisher :
- Elsevier BV, 2011.
-
Abstract
- High throughput analysis of sunscreen agents present in cream cosmetic has been demonstrated, typically 2 samples per minute, using neutral desorption extractive electrospray ionization mass spectrometry (ND-EESI-MS) without sample pretreatment. For the targeted compounds such as 4-Aminobenzoic acid and oxybenzone, ND-EESI-MS method provided linear signal responses in the range of 1-100 ppb. Limits of detection (LOD) of the method were estimated at sub-ppb levels for the analytes tested. Reasonable relative standard deviation (RSD=8.4-16.0%) was obtained as a result of 10 independent measurements for commercial cosmetics samples spiked with each individual sunscreen agents at 1-10 ppb. Acceptable recoveries were achieved in the range of 87-116% for direct analysis of commercial cream cosmetic samples. The experimental data demonstrate that ND-EESI-MS is a useful tool for high throughput screening of sunscreen agents in highly viscous cream cosmetic products, with the capability to obtain quantitative information of the analytes.
- Subjects :
- Detection limit
Spectrometry, Mass, Electrospray Ionization
Analyte
Chromatography
Emollients
media_common.quotation_subject
Sunscreen agents
Extractive electrospray ionization
Reproducibility of Results
Cosmetics
Mass spectrometry
Analytical Chemistry
Benzophenones
chemistry.chemical_compound
chemistry
Desorption
Oxybenzone
4-Aminobenzoic Acid
Sunscreening Agents
media_common
Subjects
Details
- ISSN :
- 00399140
- Volume :
- 85
- Database :
- OpenAIRE
- Journal :
- Talanta
- Accession number :
- edsair.doi.dedup.....d6a18b14f885dc5a7db5aa1f1d25ae4b