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The new steroidal glycosides from the aerial parts of Lepidogrammitis drymoglossoides
- Source :
- Journal of Asian Natural Products Research. 18:878-884
- Publication Year :
- 2016
- Publisher :
- Informa UK Limited, 2016.
-
Abstract
- Two new steroidal glycosides ponasteroside C (1) and ponasteroside D (2) were isolated from the aerial parts of Lepidogrammitis drymoglossoides. Their structures were elucidated by various spectroscopic techniques (IR, HRESIMS, 1D and 2D NMR). All compounds were evaluated for their cytotoxicity against HeLa and HCT-8 cell lines, and compounds 1 and 2 showed mild activity against all the test cell lines.
- Subjects :
- Steroidal glycosides
Stereochemistry
Pharmaceutical Science
01 natural sciences
Analytical Chemistry
HeLa
Drug Discovery
Humans
Glycosides
Cytotoxicity
Nuclear Magnetic Resonance, Biomolecular
Pharmacology
chemistry.chemical_classification
Molecular Structure
biology
010405 organic chemistry
Lepidogrammitis drymoglossoides
Organic Chemistry
Phytosterols
Glycoside
Ponasteroside D
Ponasteroside C
General Medicine
Plant Components, Aerial
biology.organism_classification
Antineoplastic Agents, Phytogenic
0104 chemical sciences
010404 medicinal & biomolecular chemistry
Complementary and alternative medicine
chemistry
Molecular Medicine
Drug Screening Assays, Antitumor
Two-dimensional nuclear magnetic resonance spectroscopy
Drugs, Chinese Herbal
HeLa Cells
Subjects
Details
- ISSN :
- 14772213 and 10286020
- Volume :
- 18
- Database :
- OpenAIRE
- Journal :
- Journal of Asian Natural Products Research
- Accession number :
- edsair.doi.dedup.....d5f7cb47f35bbb28bff5c8b1c938d6b2