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Oligonol supplementation attenuates body temperature and the circulating levels of prostaglandin E2 and cyclooxygenase-2 after heat stress in humans
- Source :
- Journal of medicinal food. 16(4)
- Publication Year :
- 2013
-
Abstract
- Oligonol, a phenolic production from lychee, has been reported to exhibit anti-oxidative and anti-inflammatory effects. This study investigated the effect of Oligonol supplementation on circulating levels of prostaglandin E2 (PGE2) and cyclooxygenase (COX)-2, as well as body temperature, after heat stress in 17 healthy human male volunteers (age, 21.6±2.1 years). All experiments were performed in an automated climate chamber (26.0°C±0.5°C, relative humidity 60%±3.0%, air velocity less than 1 m/sec) between 2 and 5 p.m. Subjects ingested an Oligonol (100 mg)-containing beverage or placebo beverage before half-body immersion into hot water (42°C±0.5°C for 30 min). Tympanic and skin temperatures were measured and mean body temperatures were calculated. Serum concentrations of PGE2 and COX-2 were analyzed before, immediately after, and 60 min after immersion. Oligonol intake significantly prevented elevation of tympanic (temperature difference: 0.17°C at Post, P
- Subjects :
- Adult
Male
medicine.medical_specialty
Hot Temperature
Medicine (miscellaneous)
Placebo
Catechin
Dinoprostone
Body Temperature
Young Adult
Litchi
Phenols
Reference Values
Stress, Physiological
Internal medicine
Immersion
medicine
Humans
Relative humidity
Temperature difference
Prostaglandin E2
Oligonol
Nutrition and Dietetics
biology
Cyclooxygenase 2 Inhibitors
Chemistry
Plant Extracts
Water
Serum concentration
Surgery
Heat stress
Endocrinology
Cyclooxygenase 2
Dietary Supplements
biology.protein
Cyclooxygenase
Skin Temperature
medicine.drug
Subjects
Details
- ISSN :
- 15577600
- Volume :
- 16
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Journal of medicinal food
- Accession number :
- edsair.doi.dedup.....d5b057e245980208fb8a6d924c458725