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Effect of bioelectrical impedance analysis-guided dry weight adjustment, in comparison to standard clinical-guided, on the sleep quality of chronic haemodialysis patients (BEDTIME study): a randomised controlled trial
- Source :
- BMC Nephrology, Vol 20, Iss 1, Pp 1-11 (2019), BMC Nephrology
- Publication Year :
- 2019
- Publisher :
- Springer Science and Business Media LLC, 2019.
-
Abstract
- Background Sleep disturbance is common among chronic haemodialysis patients, which leads to poor quality of life, in addition to increased instances of morbidity and mortality. Hypervolemia has been linked to sleep problems observed in chronic haemodialysis patients, which suggests that optimising one’s fluid status could improve the sleep quality of this patient group. In our study, we subjectively examined and objectively measured sleep parameters, using actigraphy recordings, the Pittsburgh Sleep Quality Index (PSQI) questionnaire, and Epworth Sleepiness Scale (ESS), in order to compare bioelectrical impedance analysis (BIA)-guided and standard clinical-guided dry weight adjustment. Methods We randomly selected 19 chronic haemodialysis patients with subclinical hypervolemia, defined as a clinically euvolemic status, despite the ratio of extracellular water to total body water being more than 0.4 in BIA. Furthermore, these patients, who were poor sleepers (PSQI > 5), were assigned to either a BIA-guided dry weight group (BIA group) or a standard clinical-guided one (clinical group). The primary outcome was changes in sleep actigraphy parameters between the groups at 1, 3, and 6 months. Changes observed in the PSQI and ESS score between the two groups over the same period of time were the secondary endpoints. Results The mean age of the participants was 63.53 ± 11.12 years, and 42% of them were male. All sleep parameters measured by means of actigraphy were not significantly different between the two groups. Interestingly, at 3 and 6 months, the subjective sleep quality significantly improved in the BIA group, as reflected by a greater decline in the PSQI score, in comparison with the clinical group (3 months: mean difference − 1.82 [− 3.13 to − 0.51], P = 0.006; 6 months: mean difference − 3.16 [− 4.49 to − 1.83], P
- Subjects :
- Male
Sleep Wake Disorders
medicine.medical_specialty
Polysomnography
Body water
Water-Electrolyte Imbalance
030232 urology & nephrology
Dry weight
030204 cardiovascular system & hematology
lcsh:RC870-923
Bedtime
law.invention
Pittsburgh Sleep Quality Index
03 medical and health sciences
0302 clinical medicine
Randomized controlled trial
Renal Dialysis
law
Internal medicine
Electric Impedance
medicine
Humans
Sleep disorder
business.industry
Epworth Sleepiness Scale
Body Weight
Actigraphy
Middle Aged
Sleep quality
lcsh:Diseases of the genitourinary system. Urology
medicine.disease
Haemodialysis
Treatment Outcome
Adjustment
Bioelectrical impedance analysis (BIA)
Nephrology
Quality of Life
Kidney Failure, Chronic
Female
business
Bioelectrical impedance analysis
Research Article
Subjects
Details
- ISSN :
- 14712369 and 02825589
- Volume :
- 20
- Database :
- OpenAIRE
- Journal :
- BMC Nephrology
- Accession number :
- edsair.doi.dedup.....d57bd2f140314dfa7587e4706fdef972
- Full Text :
- https://doi.org/10.1186/s12882-019-1405-z