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The cryptic IRF2BP2-RARA fusion transforms hematopoietic stem/progenitor cells and induces retinoid-sensitive acute promyelocytic leukemia
- Source :
- Leukemia, Leukemia, 2017, 31 (3), pp.747-751. ⟨10.1038/leu.2016.338⟩, Digital.CSIC. Repositorio Institucional del CSIC, instname, Leukemia, Nature Publishing Group: Open Access Hybrid Model Option B, 2017, 31 (3), pp.747-751. ⟨10.1038/leu.2016.338⟩
- Publication Year :
- 2017
- Publisher :
- HAL CCSD, 2017.
-
Abstract
- Letter to the Editor.<br />These data were presented in part at the 56th American Society of Hematology meeting, San Francisco, December 2014.
- Subjects :
- Adult
Male
0301 basic medicine
Acute promyelocytic leukemia
Cancer Research
Oncogene Proteins, Fusion
medicine.drug_class
[SDV.CAN]Life Sciences [q-bio]/Cancer
Biology
Translocation, Genetic
Fusion gene
Retinoids
03 medical and health sciences
Promyelocytic leukemia protein
0302 clinical medicine
Leukemia, Promyelocytic, Acute
medicine
Humans
Retinoid
Progenitor cell
ComputingMilieux_MISCELLANEOUS
Chromosomes, Human, Pair 15
Retinoic Acid Receptor alpha
Stem Cells
Nuclear Proteins
[SDV.MHEP.HEM]Life Sciences [q-bio]/Human health and pathology/Hematology
Hematology
Hematopoietic Stem Cells
medicine.disease
Virology
3. Good health
DNA-Binding Proteins
Leukemia
Haematopoiesis
030104 developmental biology
Oncology
030220 oncology & carcinogenesis
Cancer research
biology.protein
Stem cell
Carrier Proteins
Chromosomes, Human, Pair 17
Transcription Factors
Subjects
Details
- Language :
- English
- ISSN :
- 08876924 and 14765551
- Database :
- OpenAIRE
- Journal :
- Leukemia, Leukemia, 2017, 31 (3), pp.747-751. ⟨10.1038/leu.2016.338⟩, Digital.CSIC. Repositorio Institucional del CSIC, instname, Leukemia, Nature Publishing Group: Open Access Hybrid Model Option B, 2017, 31 (3), pp.747-751. ⟨10.1038/leu.2016.338⟩
- Accession number :
- edsair.doi.dedup.....d56a6d9e13c219c7fb95d530fef5c7a9