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Comparison of Renal Anastomosing Hemangiomas in End-Stage and Non–End-Stage Kidneys: A Meta-Analysis With a Report of 2 Cases
- Source :
- International Journal of Surgical Pathology. 25:488-496
- Publication Year :
- 2017
- Publisher :
- SAGE Publications, 2017.
-
Abstract
- Background. Renal anastomosing hemangioma (RAH) is a very rare distinct entity composed of anastomosing sinusoidal (spleen-like) capillary-sized vessels lined by flat or hobnail endothelial cells. Most of the published cases of RAH occurred in the setting of end-stage renal disease (ESRD). Methods. We present 2 cases of RAH in ESRD along with a literature review. We compared clinicopathologic features of RAHs in end-stage and non–end-stage kidneys. A meta-analysis was conducted with PubMed and a manual search through references of relevant publications. Individual patient data gathered from the literature were used in the analysis. Results. Our systematic review revealed 49 RAHs, including our 2 cases. Thirty-two (65.3%) cases were in ESRD, only 17 (34.7%) were in patients with non-ESRD. RAHs in ESRD were in younger patients, smaller in size, multifocal, and seen more with renal epithelial neoplasms when compared with RAHs in non-ESRD ( P < .05). Extramedullary hematopoiesis was seen mostly in RAHs in ESRD kidneys (85% vs 41.7%) ( P = .018). Follow-up data were available for 25 cases with a mean follow-up of 24.58 ± 38.54 months. Recurrence, metastasis, or death have never been described related to RAH in any patients. Conclusions. In conclusion, RAHs are rare and mostly arise in kidneys with end-stage damage. RAHs in ESRD and non-ESRD differ in terms of clinicopathologic features.
- Subjects :
- 0301 basic medicine
medicine.medical_specialty
medicine.medical_treatment
Disease
urologic and male genital diseases
Pathology and Forensic Medicine
Hemangioma
Young Adult
03 medical and health sciences
0302 clinical medicine
medicine
Humans
In patient
Stage (cooking)
Dialysis
business.industry
Middle Aged
medicine.disease
Kidney Neoplasms
female genital diseases and pregnancy complications
Nephrectomy
Extramedullary hematopoiesis
Surgery
030104 developmental biology
030220 oncology & carcinogenesis
Meta-analysis
Kidney Failure, Chronic
Female
Anatomy
business
Subjects
Details
- ISSN :
- 19402465 and 10668969
- Volume :
- 25
- Database :
- OpenAIRE
- Journal :
- International Journal of Surgical Pathology
- Accession number :
- edsair.doi.dedup.....d54794b2e348a7397b7a3bb1d7dd0614