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Immune Reconstitution Inflammatory Syndrome and Cytomegalovirus Pneumonia Case Report: Highlights and Missing Links in Classification Criteria and Standardized Treatment
- Source :
- Case Reports in Infectious Diseases, Vol 2017 (2017), Case Reports in Infectious Diseases
- Publication Year :
- 2017
- Publisher :
- Hindawi Limited, 2017.
-
Abstract
- Background. Cytomegalovirus (CMV) pulmonary involvement is rarely associated with IRIS; therefore, limited information is available. Case Presentation. Here, we describe the case of a 43-year-old HIV-infected male who developed an unusual case of IRIS after cytomegalovirus (CMV) pneumonia. Clinically there was a progressive and paradoxical worsening of respiratory distress, despite being treated for CMV after initiation with antiretroviral therapy. Chest X-ray revealed disseminated infiltrates in both lungs; chest CT-scan showed generalized lung involvement and mediastinal adenopathy. Pulmonary biopsy confirmed CMV pneumonia with the observation of typical viral inclusions on pneumocytes. Conclusions. CMV pneumonia can be associated with the development of IRIS requiring treatment with immunosuppressant’s and immunomodulatory drugs.
- Subjects :
- 0301 basic medicine
Unusual case
Cytomegalovirus pneumonia
medicine.diagnostic_test
Respiratory distress
business.industry
Congenital cytomegalovirus infection
virus diseases
Case Report
General Medicine
medicine.disease
Antiretroviral therapy
lcsh:Infectious and parasitic diseases
03 medical and health sciences
Pneumonia
030104 developmental biology
0302 clinical medicine
Immune reconstitution inflammatory syndrome
Immunology
Biopsy
medicine
lcsh:RC109-216
030212 general & internal medicine
business
Subjects
Details
- Language :
- English
- ISSN :
- 20906633 and 20906625
- Volume :
- 2017
- Database :
- OpenAIRE
- Journal :
- Case Reports in Infectious Diseases
- Accession number :
- edsair.doi.dedup.....d545f63f0f43fbfa69a87b4e6dc870ce