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Assessment of patients with coronary artery disease who may benefit from the use of rivaroxaban in the real world: implementation of the COMPASS trial criteria in the TERCET registry population

Authors :
Bartosz Hudzik
Mariusz Gąsior
Piotr Desperak
Source :
Polish archives of internal medicine. 129(7-8)
Publication Year :
2019

Abstract

INTRODUCTION The positive outcomes of the COMPASS trial raise questions about the proportion of patients who could benefit from additional therapy with rivaroxaban in real‑world practice. OBJECTIVES We aimed to identify the proportion of patients from the TERCET registry with significant coronary artery disease (TERCET‑CAD) who could benefit from the use of rivaroxaban and to assess their clinical characteristics and long‑term prognosis in comparison with the corresponding measures in the COMPASS trial. PATIENTS AND METHODS The COMPASS criteria were applied in the TERCET‑CAD population. Patients who met the criteria of the COMPASS trial were included in the COMPASS‑like group. The baseline characteristics and long‑term outcomes of the COMPASS‑like group were compared with the corresponding measures in the acetylsalicylic acid (ASA)-alone arm from the COMPASS trial. RESULTS The COMPASS‑like group included 3884 patients (31.6%) out of the 12 286 patients constituting the TERCET‑CAD population. Patients in the COMPASS‑like group were characterized by older age (P

Details

ISSN :
18979483
Volume :
129
Issue :
7-8
Database :
OpenAIRE
Journal :
Polish archives of internal medicine
Accession number :
edsair.doi.dedup.....d4cb9f08912343e5e363e0afb0df5552