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Alcohol dependence severity determines the course of treatmentāseeking patients
- Source :
- Alcoholism: Clinical and Experimental Research. 45:2335-2346
- Publication Year :
- 2021
- Publisher :
- Wiley, 2021.
-
Abstract
- BACKGROUND While accumulating evidence suggests a relation between the severity of alcohol dependence and the risk of its recurrence, the impact of dependence severity on the course of the disorder has not been carefully evaluated. The present study examined the impact of several severity indices of alcohol dependence on the drinking course after inpatient treatment. METHODS This prospective study was conducted over a 12-month period following alcohol treatment at a specialized hospital. A total of 712 consecutively admitted alcohol-dependent patients were targeted for enrollment at the time of their hospitalization, with 637 patients registered and followed. The characteristics and severity of the subjects were assessed using multiple methods at admission, with their course after discharge followed continuously using mailed questionnaires that queried them regarding their drinking behavior. RESULTS Greater severity of dependence, assessed using the number of ICD-10 diagnostic criteria met, was associated with a lower rate of abstinence during the study period (p = 0.035). The rate of abstinence also decreased significantly as the baseline blood gamma-glutamyl transferase value and Alcohol Dependence Scale (ADS) score increased (p = 0.031 and p = 0.0002, respectively). In multivariate Cox proportional hazards analyses, the group with the most severe ADS scores had a significantly greater risk of relapse to drinking than the group with the least severe scores (HR = 2.67, p = 0.001). Dependence severity also associated with the drinking pattern; participants in both the controlled drinking group and the abstinence group had lower ADS scores at admission and a later age at first drinking (p = 0.001 and p
- Subjects :
- Adult
Male
medicine.medical_specialty
Temperance
media_common.quotation_subject
Psychological intervention
Medicine (miscellaneous)
Motivational Interviewing
macromolecular substances
Toxicology
Severity of Illness Index
Recurrence
Internal medicine
Adaptation, Psychological
Humans
Medicine
Prospective Studies
Relapse risk
Prospective cohort study
media_common
Treatment seeking
business.industry
Proportional hazards model
Alcohol dependence
Middle Aged
Patient Acceptance of Health Care
Abstinence
Alcoholism
Psychiatry and Mental health
Treatment Outcome
Controlled drinking
Female
business
Subjects
Details
- ISSN :
- 15300277 and 01456008
- Volume :
- 45
- Database :
- OpenAIRE
- Journal :
- Alcoholism: Clinical and Experimental Research
- Accession number :
- edsair.doi.dedup.....d475957b9e8f2edf191e0e26338858a3
- Full Text :
- https://doi.org/10.1111/acer.14707