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Evaluation of contrast agent dose and diffusion coefficient measurement on vessel size index estimation
- Source :
- Magma (New York, N.Y.). 32(5)
- Publication Year :
- 2019
-
Abstract
- The goal of this study is to examine the effect of contrast agent (CA) dose and diffusion coefficient on the estimation of vessel size index (VSI). Three groups of four participants were enrolled in this study and two different experiments were performed. Different dose of CA, namely 0.1 mmol/kg and 0.05 mmol/kg were assessed in two groups of normal subjects. Diffusion coefficient effect was assessed in the third group with high-grade glioma. Imaging included gradient echo and spin-echo DSC and DTI on a 3-T MR Scanner. VSI estimation using half of standard dose of CA showed higher values compared to the application of standard, with a ratio of 2 for the WM and 1.5 for the GM. VSI estimates for tumor tissues (22 µm) were considerably higher compared to contra-lateral Normal-Appearing WM (NAWM, 4 µm, P
- Subjects :
- Adult
Magnetic Resonance Spectroscopy
media_common.quotation_subject
Biophysics
Contrast Media
030218 nuclear medicine & medical imaging
03 medical and health sciences
0302 clinical medicine
Image Processing, Computer-Assisted
Contrast (vision)
Humans
Radiology, Nuclear Medicine and imaging
Diffusion (business)
Lead (electronics)
media_common
Mathematics
Radiological and Ultrasound Technology
business.industry
Brain Neoplasms
Brain
Glioma
Middle Aged
Tumor tissue
Vessel diameter
Diffusion Magnetic Resonance Imaging
Diffusion Tensor Imaging
Blood-Brain Barrier
Blood Vessels
Nuclear medicine
business
Gradient echo
Diffusion MRI
Subjects
Details
- ISSN :
- 13528661
- Volume :
- 32
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Magma (New York, N.Y.)
- Accession number :
- edsair.doi.dedup.....d47389cac4cd8cb60e6928a5593b92b3