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Measurement of lactate accumulation byin Vivo proton NMR spectroscopy during global cerebral ischemia in rats
- Source :
- Magnetic Resonance in Medicine. 5:353-357
- Publication Year :
- 1987
- Publisher :
- Wiley, 1987.
-
Abstract
- In vivo1H NMR spectral editing techniques were used to monitor cerebral lactate production during remotely controlled temporary forebrain ischemia in rats. The lactate/N-acetylaspartate (NAA) ratio correlated with survival after ischemia and subsequent reperfusion. The lactate/NAA ratio that predicted death after ischemia in rats was estimated to be approximately 1.3. © 1987 Academic Press, Inc.
- Subjects :
- Pathology
medicine.medical_specialty
Magnetic Resonance Spectroscopy
business.industry
Ischemia
Brain
Metabolism
Pharmacology
medicine.disease
Forebrain ischemia
Brain Ischemia
Rats
Proton nmr spectroscopy
nervous system
In vivo
Lactates
Animals
Medicine
Radiology, Nuclear Medicine and imaging
business
Subjects
Details
- ISSN :
- 15222594 and 07403194
- Volume :
- 5
- Database :
- OpenAIRE
- Journal :
- Magnetic Resonance in Medicine
- Accession number :
- edsair.doi.dedup.....d46e204e7a2e8c83c160fbcc857b7382
- Full Text :
- https://doi.org/10.1002/mrm.1910050406