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Pycnogenol®-Centellicum® supplementation improves lung fibrosis and post-COVID-19 lung healing
- Source :
- Minerva medica. 113(1)
- Publication Year :
- 2021
-
Abstract
- AIM: The aim of this study was the evaluation of the combination of Pycnogenol® (150 mg/day) and Centella asiatica (Centellicum® 3 x 225 mg/day) (PY-CE) for 8 months in subjects with sequelae of idiopathic interstitial pneumonia (IIP). Recently, post-COVID-19 lung disease is emerging with large numbers of patients left with chronic lung conditions. Considering the antifibrotic activity of the combination PY-CE, we also tested this supplementary management in post-COVID-19 lung patients. RESULTS: 19 subjects with idiopathic interstitial pneumonia (IIP) were included in the study. High Resolution CT scans at inclusion confirmed the presence of lung fibrosis: 10 patients were treated with the Pycnogenol® Centellicum® combination and 9 subjects with standard management (SM) served as controls. Oxidative stress that was very high in all subjects at inclusion, decreased significantly in the supplement group (p
- Subjects :
- medicine.medical_specialty
Pulmonary Fibrosis
medicine.disease_cause
Gastroenterology
Idiopathic pulmonary fibrosis
Fibrosis
Edema
Internal medicine
medicine
Humans
Honeycombing
Idiopathic interstitial pneumonia
Lung
Flavonoids
business.industry
Plant Extracts
COVID-19
General Medicine
medicine.disease
COVID-19 Drug Treatment
Apposition
medicine.anatomical_structure
Dietary Supplements
medicine.symptom
business
Oxidative stress
Subjects
Details
- ISSN :
- 18271669
- Volume :
- 113
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Minerva medica
- Accession number :
- edsair.doi.dedup.....d44835c350ab386c17d09754cc0d3446