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Synthesis of new glycosylated neutral and cationic porphyrins dimers
- Source :
- Tetrahedron Letters, Tetrahedron Letters, 2000, 41 (3), pp.331-335. ⟨10.1016/S0040-4039(99)02085-7⟩, Tetrahedron Letters, Elsevier, 2000, 41 (3), pp.331-335. ⟨10.1016/S0040-4039(99)02085-7⟩
- Publication Year :
- 2000
- Publisher :
- HAL CCSD, 2000.
-
Abstract
- The synthesis and characterisation of symmetrical glycosylated neutral and cationic porphyrin dimers linked at the meso -position via a flexible hydrocarbon chain to improve targeting on malignant cells is reported. Photocytotoxicity of these compounds against the K562 leukemia cell line compared to the effect of hematoporphyrin is also presented.
- Subjects :
- chemistry.chemical_classification
Hematoporphyrin
010405 organic chemistry
Stereochemistry
Organic Chemistry
Cationic polymerization
010402 general chemistry
01 natural sciences
Biochemistry
Porphyrin
Leukemia cell line
0104 chemical sciences
3. Good health
carbohydrates (lipids)
chemistry.chemical_compound
Hydrocarbon
chemistry
Drug Discovery
[SDE]Environmental Sciences
polycyclic compounds
Malignant cells
ComputingMilieux_MISCELLANEOUS
K562 cells
Subjects
Details
- Language :
- English
- ISSN :
- 00404039 and 18733581
- Database :
- OpenAIRE
- Journal :
- Tetrahedron Letters, Tetrahedron Letters, 2000, 41 (3), pp.331-335. ⟨10.1016/S0040-4039(99)02085-7⟩, Tetrahedron Letters, Elsevier, 2000, 41 (3), pp.331-335. ⟨10.1016/S0040-4039(99)02085-7⟩
- Accession number :
- edsair.doi.dedup.....d441a0265f27dce9e4bd6b49fbe77ef9
- Full Text :
- https://doi.org/10.1016/S0040-4039(99)02085-7⟩