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Profile of congenital heart disease in infants born following exposure to preeclampsia
- Source :
- PLoS ONE, PLoS ONE, Vol 15, Iss 3, p e0229987 (2020)
- Publication Year :
- 2019
-
Abstract
- BackgroundEvents in pregnancy play an important role in predisposing the newborn to the risk of developing CHD. This study evaluated the association between maternal preeclampsia and her offspring risk of CHD.MethodsThis is a cohort study of 90 sex-matched neonates (45 each born to women with preeclampsia and normal pregnancy) in Jos, Nigeria. Anthropometry was taken shortly after delivery using standard protocols. Echocardiography was performed within 24 hours of life and repeated 7 and 28 days later. SPSS version 25 was used in all analyses. Statistical significance was set at pResultsCongenital heart disease (CHD) was observed in 27 (30.0%) of newborns of women with preeclampsia compared with 11 (12.1%) of newborns without preeclampsia (pConclusionCHD may be more common in newborns of women with preeclampsia underscoring the need for fetal and newborn screening for CHD in women with preeclampsia so as to improve their infant's well being.
- Subjects :
- Male
Heart disease
Maternal Health
030204 cardiovascular system & hematology
Cardiovascular Medicine
Labor and Delivery
Families
0302 clinical medicine
Pre-Eclampsia
Pregnancy
Medicine and Health Sciences
Morphogenesis
Children
reproductive and urinary physiology
030219 obstetrics & reproductive medicine
Multidisciplinary
Obstetrics
Obstetrics and Gynecology
Congenital Heart Defects
female genital diseases and pregnancy complications
3. Good health
Cardiovascular Diseases
embryonic structures
Medicine
Female
Infants
Cohort study
Research Article
Adult
Heart Defects, Congenital
medicine.medical_specialty
Offspring
Science
Cardiology
Risk Assessment
Preeclampsia
03 medical and health sciences
medicine
Congenital Disorders
Cardiovascular Diseases in Women
Humans
Birth Defects
Newborn screening
business.industry
Infant, Newborn
Infant
Biology and Life Sciences
Neonates
Anthropometry
medicine.disease
Pregnancy Complications
Age Groups
People and Places
Patent foramen ovale
Birth
Ventricular Septal Defects
Women's Health
Population Groupings
business
Developmental Biology
Subjects
Details
- ISSN :
- 19326203
- Volume :
- 15
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- PloS one
- Accession number :
- edsair.doi.dedup.....d42f698890b4536544761bee5d19510f