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Sex chromosomes: evolving dosage compensation

Authors :
Brian Charlesworth
Source :
Current biology : CB. 8(25)
Publication Year :
1999

Abstract

Dosage compensation of some X-linked genes varies among mammals. Inactivation of an X-linked copy of a gene in females appears to correlate with lack of an active homologue on the Y chromosome, implying that dosage compensation evolves in response to the loss of function of genes on the Y.

Details

ISSN :
09609822
Volume :
8
Issue :
25
Database :
OpenAIRE
Journal :
Current biology : CB
Accession number :
edsair.doi.dedup.....d41e96000f464bfa1d26cb2a358d7343