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A facile method for urinary phenylalanine measurement on paper-based lab-on-chip for PKU therapy monitoring
- Source :
- The Analyst. 142:4629-4632
- Publication Year :
- 2017
- Publisher :
- Royal Society of Chemistry (RSC), 2017.
-
Abstract
- A miniaturized paper-based lab-on-chip (LoC) was developed for the facile measurement of urinary Phe (phenylalanine) level on PKU (Phenylketonuria) treated patient. This system permits the monitoring of Phe in a dynamic range concentration of 20-3000 μM.
- Subjects :
- Paper
congenital, hereditary, and neonatal diseases and abnormalities
Phenylalanine
Urinary system
02 engineering and technology
01 natural sciences
Biochemistry
Analytical Chemistry
law.invention
law
Lab-On-A-Chip Devices
Phenylketonurias
Electrochemistry
Humans
Environmental Chemistry
Spectroscopy
Treated patient
TANDEM MASS-SPECTROMETRY, BLOOD PHENYLALANINE, HYDROXYLASE DEFICIENCY, PHENYLKETONURIA, BIOSENSOR, METAANALYSIS, SYSTEM
Hematologic Tests
Chromatography
Chemistry
010401 analytical chemistry
nutritional and metabolic diseases
Phenylalanine measurement
Paper based
Lab-on-a-chip
021001 nanoscience & nanotechnology
0104 chemical sciences
Therapy monitoring
0210 nano-technology
Subjects
Details
- ISSN :
- 13645528 and 00032654
- Volume :
- 142
- Database :
- OpenAIRE
- Journal :
- The Analyst
- Accession number :
- edsair.doi.dedup.....d3c62e8a5e961c9b1a94b7007d476387