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Comparison of two methods for tumour-targeting peptide modification of liposomes

Authors :
Shi-Qi, Huang
Han-Ming, Zhang
Yi-Cong, Zhang
Lu-Yao, Wang
Zhi-Rong, Zhang
Ling, Zhang
Source :
Acta Pharmacologica Sinica. 44:832-840
Publication Year :
2022
Publisher :
Springer Science and Business Media LLC, 2022.

Abstract

Liposomes decorated with tumour-targeting cell-penetrating peptides can enhance specific drug delivery at the tumour site. The TR peptide, c(RGDfK)-AGYLLGHINLHHLAHL(Aib)HHIL, is pH-sensitive and actively targets tumour cells that overexpress integrin receptor α

Details

ISSN :
17457254 and 16714083
Volume :
44
Database :
OpenAIRE
Journal :
Acta Pharmacologica Sinica
Accession number :
edsair.doi.dedup.....d3b34aeeff27435b8760aaade18f0d4f