Mechanisms underlying Nrf2 nuclear translocation by non-lethal levels of hydrogen peroxide: p38 MAPK-dependent neutral sphingomyelinase2 membrane trafficking and ceramide/PKCζ/CK2 signaling

Authors :: Tetsuro Ishii
Eiji Warabi
Giovanni E. Mann
Source :: Free Radical Biology and Medicine. 191:191-202
Publication Year :: 2022
Publisher :: Elsevier BV, 2022.
Abstract: Hydrogen peroxide is an aerobic metabolite playing a central role in redox signaling and oxidative stress. H

Subjects :: Kelch-Like ECH-Associated Protein 1
NF-E2-Related Factor 2
Caveolin 1
NF-kappa B
Hydrogen Peroxide
Ceramides
GA-Binding Protein Transcription Factor
Glutathione
p38 Mitogen-Activated Protein Kinases
Biochemistry
Transcription Factor AP-1
Oxidative Stress
Sphingomyelin Phosphodiesterase
Peroxidases
Physiology (medical)
Casein Kinase II

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